Malignant Brain Tumors In Children Will Soon Be Able To Be Curable.
A opening den has found that a targeted treatment for medulloblastoma - the most frequent malignant brain cancer in children - may one day be able to treat drug-resistant forms of the disease. "Less than 5 percent of patients currently continue medulloblastoma," said Dr Amar Gajjar, advance author of the study, which was presented Saturday at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago drugstore. "Most patients in the main die 12 to 18 months after the tumor comes back".
Although this contemplation was designed primarily to assess team effects, if the drug moves through the pharmaceutical pipeline, it would be the first targeted drug aimed at a signaling pathway. Chemotherapy is the utter treatment now incense. The drug, known as GDC-0449, interrupts the "sonic hedgehog" pathway, which has been implicated in a thousand of other cancers; it is involved in 20 percent of cases of children with medulloblastoma.
